Reprogramming the genetic code

The encoded biosynthesis of proteins provides the ultimate paradigm for high-fidelity synthesis of long polymers of defined sequence and composition, but it is limited to polymerizing the canonical amino acids. Recent advances have built on genetic code expansion — which commonly permits the cellula...

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Veröffentlicht in:	Nature reviews. Genetics 2021-03, Vol.22 (3), p.169-184
Hauptverfasser:	de la Torre, Daniel, Chin, Jason W.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/1511 631/553/552 631/61 Agriculture Amino acids Amino Acids - genetics Animal Genetics and Genomics Animals Biomedical and Life Sciences Biomedicine Biopolymers Cancer Research Cellular Reprogramming - genetics Codon - genetics Codons DNA - genetics Gene Function Genetic aspects Genetic code Genetic Code - genetics Genetic research Genomes Human Genetics Humans Production processes Protein biosynthesis Protein Biosynthesis - genetics Proteins - genetics Review Article
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