Membrane Remodeling: ESCRT-III Filaments as Molecular Garrotes

Membrane Remodeling: ESCRT-III Filaments as Molecular Garrotes

New reconstitution, biochemical and structural studies are revealing how the core machinery of the ESCRT pathway constricts membranes to promote fission. Equally exciting is the discovery and characterization of conserved ESCRT-like machinery across all three domains of life. New reconstitution, bio...

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Veröffentlicht in:Current biology 2020-12, Vol.30 (23), p.R1425-R1428
Hauptverfasser: McCullough, John, Sundquist, Wesley I.
Format: Artikel
Sprache:eng
Schlagworte:
Cytoskeleton
Endosomal Sorting Complexes Required for Transport - genetics
Polymerization
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Zusammenfassung:New reconstitution, biochemical and structural studies are revealing how the core machinery of the ESCRT pathway constricts membranes to promote fission. Equally exciting is the discovery and characterization of conserved ESCRT-like machinery across all three domains of life. New reconstitution, biochemical and structural studies are revealing how the core machinery of the ESCRT pathway constricts membranes to promote fission. Equally exciting is the discovery and characterization of conserved ESCRT-like machinery across all three domains of life.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2020.09.086