Association of perceived stress with health status outcomes in patients with peripheral artery disease
To assess association of chronic self-perceived stress with health status outcomes of patients with peripheral artery disease. The PORTRAIT study is a prospective registry that enrolled 1275 patients with symptoms of peripheral artery disease across 16-sites in US, Netherlands, and Australia from Ju...
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Veröffentlicht in: | Journal of psychosomatic research 2021-01, Vol.140, p.110313-110313, Article 110313 |
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Sprache: | eng |
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Zusammenfassung: | To assess association of chronic self-perceived stress with health status outcomes of patients with peripheral artery disease.
The PORTRAIT study is a prospective registry that enrolled 1275 patients with symptoms of peripheral artery disease across 16-sites in US, Netherlands, and Australia from June 2011 to December 2015. Demographics, comorbidities and diagnostic information was abstracted from chart review. Self-perceived stress was assessed using the 4-item perceived stress scale at baseline, 3- and 6-month follow-up. Scores range from 0 to 16 with higher scores indicating greater stress. Sum scores were calculated at each time point and averaged to quantify average exposure to stress from enrollment through 6 months. Disease-specific health status were assessed at baseline and 12-months using the peripheral artery disease questionnaire summary score.
The mean age of the analytical cohort (n = 1060) was 67.7 ± 9.3 years, 37.1% were females, and 82.3% were white. Comorbidities were highly prevalent with 80.9% having hypertension, 32.6% having diabetes, and 36.4% being smokers. In models adjusted for demographics, comorbidities, disease severity and socioeconomic status, having a higher average stress score was associated with poorer recovery (from baseline) in peripheral artery disease questionnaire summary score at 12-months (−1.4 points per +1-point increase in averaged 4-point perceived stress score, 95% CI -2.1, −0.6 p |
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ISSN: | 0022-3999 1879-1360 |
DOI: | 10.1016/j.jpsychores.2020.110313 |