Evaluation of trappin‐2 in cervicovaginal secretions as predictor of spontaneous preterm birth in asymptomatic high‐risk women: Nested case‐control study

Objective To evaluate trappin‐2 levels in cervicovaginal secretions for prediction of spontaneous preterm birth (sPTB) and compare it with transvaginal sonography (TVS) cervical length in asymptomatic women at risk of PTB. Methods Trappin‐2 levels assessed in cervicovaginal secretions collected from 80 asymptomatic pregnant women at high risk for preterm delivery and cervical length measured by TVS, first at 14–20 weeks of pregnancy and repeated 8 weeks later. On the basis of delivery outcomes, participants were divided into cases (delivery