Autophagy Brings an END to Aberrant Endocytosis

Autophagy Brings an END to Aberrant Endocytosis

Wilfling et al. (2020) characterize a selective autophagy pathway in yeast for early clathrin-mediated endocytosis (CME) proteins facilitated by the phase separation of the CME protein, Ede1, which acts as an intrinsic autophagy receptor for the degradation of Ede1-dependent endocytic protein deposi...

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Veröffentlicht in:Molecular cell 2020-12, Vol.80 (5), p.758-759
Hauptverfasser: Makar, Agata N., Gammoh, Noor
Format: Artikel
Sprache:eng
Schlagworte:
Autophagy
Clathrin
Endocytosis
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae Proteins - genetics
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Zusammenfassung:Wilfling et al. (2020) characterize a selective autophagy pathway in yeast for early clathrin-mediated endocytosis (CME) proteins facilitated by the phase separation of the CME protein, Ede1, which acts as an intrinsic autophagy receptor for the degradation of Ede1-dependent endocytic protein deposits (ENDs). Wilfling et al. (2020) characterize a selective autophagy pathway in yeast for early clathrin-mediated endocytosis (CME) proteins facilitated by the phase separation of the CME protein, Ede1, which acts as an intrinsic autophagy receptor for the degradation of Ede1-dependent endocytic protein deposits (ENDs).
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2020.11.020