“Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina

In late 2018, Andes virus was identified as the cause of an outbreak of hantavirus pulmonary syndrome in Argentina. This outbreak was associated with 34 confirmed infections and 11 deaths. A detailed investigation identified person-to-person transmission that was driven by three symptomatic persons.

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Veröffentlicht in:	The New England journal of medicine 2020-12, Vol.383 (23), p.2230-2241
Hauptverfasser:	Martínez, Valeria P, Di Paola, Nicholas, Alonso, Daniel O, Pérez-Sautu, Unai, Bellomo, Carla M, Iglesias, Ayelén A, Coelho, Rocio M, López, Beatriz, Periolo, Natalia, Larson, Peter A, Nagle, Elyse R, Chitty, Joseph A, Pratt, Catherine B, Díaz, Jorge, Cisterna, Daniel, Campos, Josefina, Sharma, Heema, Dighero-Kemp, Bonnie, Biondo, Emiliano, Lewis, Lorena, Anselmo, Constanza, Olivera, Camila P, Pontoriero, Fernanda, Lavarra, Enzo, Kuhn, Jens H, Strella, Teresa, Edelstein, Alexis, Burgos, Miriam I, Kaler, Mario, Rubinstein, Adolfo, Kugelman, Jeffrey R, Sanchez-Lockhart, Mariano, Perandones, Claudia, Palacios, Gustavo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Argentina - epidemiology Blood Chemical Analysis Carrier State Contact tracing Coronaviruses Cytokines Disease Outbreaks Disease transmission Epidemics Epidemiology Female Genomes Hantavirus Hantavirus - genetics Hantavirus pulmonary syndrome Hantavirus Pulmonary Syndrome - epidemiology Hantavirus Pulmonary Syndrome - mortality Hantavirus Pulmonary Syndrome - transmission Hantavirus Pulmonary Syndrome - virology Haplotypes High-Throughput Nucleotide Sequencing Humans Infections Laboratories Male Middle Aged Next-generation sequencing Outbreaks Patients Phylogenetics Phylogeny Public health Rodentia Severe acute respiratory syndrome coronavirus 2 Viral Load Young Adult Zoonoses
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Zusammenfassung:	In late 2018, Andes virus was identified as the cause of an outbreak of hantavirus pulmonary syndrome in Argentina. This outbreak was associated with 34 confirmed infections and 11 deaths. A detailed investigation identified person-to-person transmission that was driven by three symptomatic persons.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2009040