Therapeutic Drug Level Monitoring of Teicoplanin in Korean Pediatric Patients with Normal versus Impaired Renal Function

Background: Teicoplanin is used to treat serious gram-positive infections. Optimal teicoplanin trough levels are considered to be >= 10 mu g/mL. Despite its wide use in various clinical settings, data on teicoplanin trough level in pediatric patients are limited. Therefore, the aim of this study...

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Veröffentlicht in:Journal of Korean medical science 2020, 35(46), , pp.1-10
Hauptverfasser: Choi, Joon-sik, Kim, Jong Min, Kim, Dongsub, Kim, Si-Ho, Cho, Heeyeon, Park, Hyung-Doo, Lee, Soo-Youn, Kang, Cheol-In, Kim, Yae-Jean
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Sprache:eng
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Zusammenfassung:Background: Teicoplanin is used to treat serious gram-positive infections. Optimal teicoplanin trough levels are considered to be >= 10 mu g/mL. Despite its wide use in various clinical settings, data on teicoplanin trough level in pediatric patients are limited. Therefore, the aim of this study was to investigate the therapeutic drug level monitoring of teicoplanin in Korean pediatric patients, including those with impaired renal function. Methods: A retrospective study was performed in pediatric patients (age
ISSN:1011-8934
1598-6357
DOI:10.3346/jkms.2020.35.e376