Cancer cell-targeted nanoprobe for multilayer imaging of diverse biomarkers and precise photodynamic therapy

Cancer cell-targeted nanoprobe for multilayer imaging of diverse biomarkers and precise photodynamic therapy

A novel multifunctional nanoprobe was designed for cancer cell targeted multilayer imaging of two cancer biomarkers. Based on the proposed method, in situ imaging of membrane MUC1 mucin and cytoplasmic microRNA miR-21 coupled with precise photodynamic therapy was achieved. A novel multifunctional na...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-12, Vol.56 (96), p.1528-15211
Hauptverfasser: Fu, Zhuolin, Wu, Yingdi, Ren, Chunnian, Song, Weiling, Zhang, Xiaoru, Yue, Meie, Li, Ying
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Cancer
Chemistry
Chemistry, Multidisciplinary
Imaging
Multilayers
Photodynamic therapy
Physical Sciences
Ribonucleic acid
RNA
Science & Technology
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Zusammenfassung:A novel multifunctional nanoprobe was designed for cancer cell targeted multilayer imaging of two cancer biomarkers. Based on the proposed method, in situ imaging of membrane MUC1 mucin and cytoplasmic microRNA miR-21 coupled with precise photodynamic therapy was achieved. A novel multifunctional nanoprobe was designed for cancer cell targeted multilayer imaging of two cancer biomarkers. And in situ imaging of membrane MUC1 mucin and cytoplasmic microRNA miR-21 coupled with precise photodynamic therapy was achieved.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc06305c