Parietal Convexity Meningeal Melanocytoma: Radiologic–Pathologic Correlation

Supratentorial lesions are rare.1,2 Few examples of convexity meningeal melanocytomas have been documented in the literature.1,3,4 Annual incidence of meningeal melanocytoma is 1 per 10 million, and females have been reported to be affected twice as frequently.5 Peak presentation is in the fourth an...

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Veröffentlicht in:Canadian journal of neurological sciences 2021-09, Vol.48 (5), p.719-721
Hauptverfasser: Chan, Ian Y. M., Li, Hao, Shi, Thomas, Hammond, Robert R., Jurkiewicz, Michael T.
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container_issue 5
container_start_page 719
container_title Canadian journal of neurological sciences
container_volume 48
creator Chan, Ian Y. M.
Li, Hao
Shi, Thomas
Hammond, Robert R.
Jurkiewicz, Michael T.
description Supratentorial lesions are rare.1,2 Few examples of convexity meningeal melanocytomas have been documented in the literature.1,3,4 Annual incidence of meningeal melanocytoma is 1 per 10 million, and females have been reported to be affected twice as frequently.5 Peak presentation is in the fourth and fifth decades, and it very rarely occurs in children.1,6 Depending on the location of the tumor, patients may present with myelopathy, radiculopathy, cranial nerve deficits, hydrocephalus, or, as in our case, seizures.7 Preoperative diagnosis of meningeal melanocytoma often proves difficult as the clinical and radiological features of the tumor are nonspecific. On histology, meningeal melanocytomas display minimal nuclear pleomorphism, atypia, and macronucleoli in contrast to metastatic melanomas. [...]mitotic figures and necrosis are typically absent in melanocytomas. Without gross total resection, the recurrence rate increases to approximately 50%.9 Therefore, adjuvant radiation therapy is often recommended, especially with incomplete resection.10 Statement of Authorship IYMC contributed to the case description, literature review, radiology images and descriptions, as well as the drafting and revision of the manuscript.
doi_str_mv 10.1017/cjn.2020.256
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M. ; Li, Hao ; Shi, Thomas ; Hammond, Robert R. ; Jurkiewicz, Michael T.</creator><creatorcontrib>Chan, Ian Y. M. ; Li, Hao ; Shi, Thomas ; Hammond, Robert R. ; Jurkiewicz, Michael T.</creatorcontrib><description>Supratentorial lesions are rare.1,2 Few examples of convexity meningeal melanocytomas have been documented in the literature.1,3,4 Annual incidence of meningeal melanocytoma is 1 per 10 million, and females have been reported to be affected twice as frequently.5 Peak presentation is in the fourth and fifth decades, and it very rarely occurs in children.1,6 Depending on the location of the tumor, patients may present with myelopathy, radiculopathy, cranial nerve deficits, hydrocephalus, or, as in our case, seizures.7 Preoperative diagnosis of meningeal melanocytoma often proves difficult as the clinical and radiological features of the tumor are nonspecific. On histology, meningeal melanocytomas display minimal nuclear pleomorphism, atypia, and macronucleoli in contrast to metastatic melanomas. [...]mitotic figures and necrosis are typically absent in melanocytomas. Without gross total resection, the recurrence rate increases to approximately 50%.9 Therefore, adjuvant radiation therapy is often recommended, especially with incomplete resection.10 Statement of Authorship IYMC contributed to the case description, literature review, radiology images and descriptions, as well as the drafting and revision of the manuscript.</description><identifier>ISSN: 0317-1671</identifier><identifier>EISSN: 2057-0155</identifier><identifier>DOI: 10.1017/cjn.2020.256</identifier><identifier>PMID: 33213533</identifier><language>eng</language><publisher>New York, USA: Cambridge University Press</publisher><subject>Brain cancer ; Case reports ; Embolization ; Hemorrhage ; Histology ; Literature reviews ; Magnetic resonance imaging ; Melanoma ; Metastasis ; Neuroimaging Highlights ; Pathology ; Polyvinyl alcohol ; Radiation therapy ; Skin cancer ; Tumors</subject><ispartof>Canadian journal of neurological sciences, 2021-09, Vol.48 (5), p.719-721</ispartof><rights>Copyright © The Author(s), 2020. 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subjects Brain cancer
Case reports
Embolization
Hemorrhage
Histology
Literature reviews
Magnetic resonance imaging
Melanoma
Metastasis
Neuroimaging Highlights
Pathology
Polyvinyl alcohol
Radiation therapy
Skin cancer
Tumors
title Parietal Convexity Meningeal Melanocytoma: Radiologic–Pathologic Correlation
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