Parietal Convexity Meningeal Melanocytoma: Radiologic–Pathologic Correlation

Supratentorial lesions are rare.1,2 Few examples of convexity meningeal melanocytomas have been documented in the literature.1,3,4 Annual incidence of meningeal melanocytoma is 1 per 10 million, and females have been reported to be affected twice as frequently.5 Peak presentation is in the fourth an...

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Veröffentlicht in:Canadian journal of neurological sciences 2021-09, Vol.48 (5), p.719-721
Hauptverfasser: Chan, Ian Y. M., Li, Hao, Shi, Thomas, Hammond, Robert R., Jurkiewicz, Michael T.
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Sprache:eng
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Zusammenfassung:Supratentorial lesions are rare.1,2 Few examples of convexity meningeal melanocytomas have been documented in the literature.1,3,4 Annual incidence of meningeal melanocytoma is 1 per 10 million, and females have been reported to be affected twice as frequently.5 Peak presentation is in the fourth and fifth decades, and it very rarely occurs in children.1,6 Depending on the location of the tumor, patients may present with myelopathy, radiculopathy, cranial nerve deficits, hydrocephalus, or, as in our case, seizures.7 Preoperative diagnosis of meningeal melanocytoma often proves difficult as the clinical and radiological features of the tumor are nonspecific. On histology, meningeal melanocytomas display minimal nuclear pleomorphism, atypia, and macronucleoli in contrast to metastatic melanomas. [...]mitotic figures and necrosis are typically absent in melanocytomas. Without gross total resection, the recurrence rate increases to approximately 50%.9 Therefore, adjuvant radiation therapy is often recommended, especially with incomplete resection.10 Statement of Authorship IYMC contributed to the case description, literature review, radiology images and descriptions, as well as the drafting and revision of the manuscript.
ISSN:0317-1671
2057-0155
DOI:10.1017/cjn.2020.256