Effectiveness of short vs long‐course perioperative antibiotics in lung transplant recipients with donor positive respiratory cultures

Lung transplant recipients are at increased risk for infection in the early postoperative phase, thus perioperative antibiotics are employed. This retrospective study evaluated the efficacy of short‐ vs long‐course perioperative antibiotics in lung transplant patients. Lung transplant patients with...

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Veröffentlicht in:Transplant infectious disease 2021-06, Vol.23 (3), p.e13518-n/a
Hauptverfasser: Groff, Lindsey T., Reed, Erica E., Coe, Kelci E., El Boghdadly, Zeinab, Keller, Brian C., Whitson, Bryan A., Burcham, Pamela K.
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Sprache:eng
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Zusammenfassung:Lung transplant recipients are at increased risk for infection in the early postoperative phase, thus perioperative antibiotics are employed. This retrospective study evaluated the efficacy of short‐ vs long‐course perioperative antibiotics in lung transplant patients. Lung transplant patients with donor positive cultures between August 2013 and September 2019 were evaluated, excluding those with cystic fibrosis, death within 14 days and re‐transplants. The primary outcome was 30‐day freedom from donor‐derived respiratory infection. A total of 147 patients were included (57 short vs 90 long‐course). Median perioperative antibiotic duration was 6 days in the short‐course vs 14 days in the long‐course group (P 
ISSN:1398-2273
1399-3062
DOI:10.1111/tid.13518