First report of the aac(6 ')-Ib-cr gene in Providencia stuartii isolates in Brazil

Introduction: The aac(6')-Ib-cr and bla(KPC) genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. Methods: These genes were investigated in 28 P stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing. Results: The aac(6')-Ib-cr gene was detected in 16 resistant isolates, and the bla(KPC) gene was seen in 14. Conclusions: The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.