Endometrial Cancer

Endometrial carcinoma is diagnosed in about 58,500 women in the United States per year. It is linked with obesity, excess estrogen, and the Lynch syndrome. Oral contraceptives lower the risk by 30 to 40%. Most patients undergo surgery with or without radiation therapy.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2020-11, Vol.383 (21), p.2053-2064
Hauptverfasser:	Lu, Karen H, Broaddus, Russell R
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age of Onset Body Mass Index Carcinoma Colorectal cancer Colorectal Neoplasms, Hereditary Nonpolyposis - complications Combined Modality Therapy Disease prevention Endometrial cancer Endometrial Neoplasms - epidemiology Endometrial Neoplasms - genetics Endometrial Neoplasms - pathology Endometrial Neoplasms - therapy Endometrium Epidemiology Estrogens Female Gene expression Genetic disorders Hormone replacement therapy Humans Hysterectomy Hysterectomy - methods Kinases Medical prognosis Mortality Mutation Neoplasm Staging Obesity Obesity - complications Oral contraceptives Radiation therapy Surgery Tumors Uterine cancer Uterine Neoplasms - ethnology Uterus
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Beschreibung
Zusammenfassung:	Endometrial carcinoma is diagnosed in about 58,500 women in the United States per year. It is linked with obesity, excess estrogen, and the Lynch syndrome. Oral contraceptives lower the risk by 30 to 40%. Most patients undergo surgery with or without radiation therapy.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMra1514010