Esophageal Motility Disorders and Gastroesophageal Reflux Disease

Esophageal Motility Disorders and Gastroesophageal Reflux Disease

Esophageal motility disorders and esophageal reflux are common, produce a wide range of symptoms, and compromise quality of life. Neural and muscle-based mechanisms contribute to altered function of the lower esophageal sphincter, creating problems if it is too relaxed or too constricted. Improvemen...

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Veröffentlicht in:The New England journal of medicine 2020-11, Vol.383 (20), p.1961-1972
Hauptverfasser: Mittal, Ravinder, Vaezi, Michael F
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Diaphragm (Anatomy)
Disease
Dysphagia
Esophageal diseases
Esophageal sphincter
Esophagus
Gastroesophageal reflux
Motility
Muscle contraction
Pain
Pathogenesis
Patients
Quality of life
Scleroderma
Smooth muscle
Sphincter
Stomach
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Beschreibung
Zusammenfassung:Esophageal motility disorders and esophageal reflux are common, produce a wide range of symptoms, and compromise quality of life. Neural and muscle-based mechanisms contribute to altered function of the lower esophageal sphincter, creating problems if it is too relaxed or too constricted. Improvements in diagnosis and treatment have improved the management of these disorders.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMra2000328