Unexpected tunnelled central venous access demise: a single institutional study from the UK

Unexpected tunnelled central venous access demise: a single institutional study from the UK

Purpose To explore the factors involved in the demise of tunnelled central vascular access devices (CVADs) in children and describe patterns of failure. Methods A retrospective study including children under 16 years of age undergoing CVAD insertion in a tertiary centre between October 2014 and Dece...

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Veröffentlicht in:Pediatric surgery international 2021, Vol.37 (1), p.109-117
Hauptverfasser: Bough, Georgina, Lambert, Nicholas J., Djendov, Florin, Jackson, Claire
Format: Artikel
Sprache:eng
Schlagworte:
Age
Catheters
Chemotherapy
Children & youth
Cost control
Hospitals
Infections
Medicine
Medicine & Public Health
Original Article
Pediatric Surgery
Pediatrics
Statistical analysis
Surgeons
Surgery
Venous access
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Zusammenfassung:Purpose To explore the factors involved in the demise of tunnelled central vascular access devices (CVADs) in children and describe patterns of failure. Methods A retrospective study including children under 16 years of age undergoing CVAD insertion in a tertiary centre between October 2014 and December 2019. The Kaplan–Meier estimator was used to study CVAD survival and piecewise exponential curves to approximate hazard rates. Related factors were analysed using multivariable regression. Results Totally, 684 CVADs were inserted in 499 children. Devices were in situ for 213,821 days (median 244.5). Of those, 261 CVADs (38.2%) failed prematurely; 176 (67%) required replacement. Tunnelled external lines (TELs) failed more frequently than totally implantable devices ( p  
ISSN:0179-0358
1437-9813
DOI:10.1007/s00383-020-04771-4