An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019

An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019

We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye...

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Veröffentlicht in:Journal of medical virology 2021-06, Vol.93 (6), p.3969-3973
Hauptverfasser: Toovey, Oliver T. R., Kulkarni, Priti, David, Joicy, Patel, Ayushi, Lai, Florence Y., Burns, Joyce, Thompson, Catherine, Ellis, Joanna, Tang, Julian W.
Format: Artikel
Sprache:eng
Schlagworte:
adenovirus
Adenoviruses
community
Epidemics
Eye diseases
incidence
Keratitis
Keratoconjunctivitis
nosocomial
outbreak
Short Communication
Short Communications
Species
transmission
Virology
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Beschreibung
Zusammenfassung:We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.26647