Usefulness of handheld electroretinogram system for diagnosing blue-cone monochromatism in children
Purpose To report the diagnosis of three childhood patients with blue-cone monochromatism (BCM) using S-cone electroretinograms (ERG) recorded with RETeval ® Complete. Study design Prospective clinical study. Methods We examined three boys initially suspected of having rod monochromatism. S-cone ERG...
Gespeichert in:
Veröffentlicht in: | Japanese journal of ophthalmology 2021-01, Vol.65 (1), p.23-29 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Purpose
To report the diagnosis of three childhood patients with blue-cone monochromatism (BCM) using S-cone electroretinograms (ERG) recorded with RETeval
®
Complete.
Study design
Prospective clinical study.
Methods
We examined three boys initially suspected of having rod monochromatism. S-cone ERG was performed with red background and blue flashed light stimulation using two different intensities: 0.25 cd × s/m
2
and 1 cd × s/m
2
.
Results
Case 1 was a 12-year-old boy with a visual acuity of 0.1 OU. Case 2 was an 8-year-old boy with a visual acuity of 0.3 OD and 0.2 OS. Both cases showed a myopic fundus and nystagmus without any other ocular abnormalities. Case 3 was a 6-year-old boy with a visual acuity of 0.3 OD and 0.4 OS. He also showed myopic fundus changes, but nystagmus was not observed. Rod and maximal responses recorded with RETeval
®
were likely to be within normal range; however, cone responses were absent in all cases. S-cone ERGs showed positive responses at 40 ms with 0.25 cd × s/m
2
intensity in Case 2, and at approximately 30–40 ms with 1.0 cd × s/m
2
intensity in all three cases. These ERG findings led to a diagnosis of BCM.
Conclusions
S-cone ERG of RETeval
®
was helpful in diagnosing with minimal invasion BCM in childhood patients. |
---|---|
ISSN: | 0021-5155 1613-2246 |
DOI: | 10.1007/s10384-020-00782-9 |