Porto-sinusoidal vascular disease with portal hypertension versus liver cirrhosis: differences in imaging features on CT and hepatobiliary contrast-enhanced MRI

Purpose To differentiate the computed tomography (CT) and magnetic resonance imaging (MRI) features of porto-sinusoidal vascular disease (PSVD) and liver cirrhosis (LC). Methods In this retrospective case–control study of patients with PSVD matched in a 1:3 ratio with LC patients according to liver...

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Veröffentlicht in:Abdominal imaging 2021-05, Vol.46 (5), p.1891-1903
Hauptverfasser: Kang, Ji Hun, Kim, Do Hyung, Kim, So Yeon, Kang, Hyo Jeong, Lee, Jung Bok, Kim, Kyoung Won, Lee, Seung Soo, Choi, Jonggi, Lim, Young-Suk
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Sprache:eng
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Zusammenfassung:Purpose To differentiate the computed tomography (CT) and magnetic resonance imaging (MRI) features of porto-sinusoidal vascular disease (PSVD) and liver cirrhosis (LC). Methods In this retrospective case–control study of patients with PSVD matched in a 1:3 ratio with LC patients according to liver function, initial diagnosis and time to final diagnosis were analyzed. Imaging features on CT and the parenchymal enhancement on hepatobiliary phase of hepatobiliary agent-enhanced MRI (HBA-MRI) were compared using a generalized linear mixed model. Focal hepatic lesions in the PSVD group were analyzed. Results In total, 43 PSVD patients and 129 LC patients were included. Among PSVD patients, 72.1% were initially misdiagnosed with LC. PSVD patients had a longer diagnostic delay than LC patients (32 months vs. 4 months; p  
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-020-02831-w