Experimental Modeling of Leprosy in BALB/c, BALB/c Nude, CBA, and C57BL/6ТNF—/— Mice
Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF —/— mice using three Mycobacterium leprae strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of M. leprae of the used strains showed...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2020-10, Vol.169 (6), p.836-839 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Karamova, A. E. Semenova, V. G. Verbenko, D. A. Obraztsova, O. A. Vanchugova, Kh. M. Nikonorov, A. A. Deryabin, D. G. Solomka, V. S. Kubanov, A. A. |
| description | Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF
—/—
mice using three
Mycobacterium leprae
strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of
M. leprae
of the used strains showed a temporal-quantitative dependence on the used mouse line. CBA and BALB/cNude mice were optimal for strain R and BALB/c and BALB/cNude lines were optimal for strain I. BALB/cNude mice infected with strain I had low lifespan.
M. leprae
strain M showed low proliferation activity in BALB/cNude and C57BL/6ТNF
—/—
mice. |
| doi_str_mv | 10.1007/s10517-020-04991-7 |
| format | Article |
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—/—
mice using three
Mycobacterium leprae
strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of
M. leprae
of the used strains showed a temporal-quantitative dependence on the used mouse line. CBA and BALB/cNude mice were optimal for strain R and BALB/c and BALB/cNude lines were optimal for strain I. BALB/cNude mice infected with strain I had low lifespan.
M. leprae
strain M showed low proliferation activity in BALB/cNude and C57BL/6ТNF
—/—
mice.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-020-04991-7</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Cell Biology ; Internal Medicine ; Laboratory Medicine ; Leprosy ; Life span ; Methods ; Pathology</subject><ispartof>Bulletin of experimental biology and medicine, 2020-10, Vol.169 (6), p.836-839</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2187-85876f7ee9c3ac2f6b044bb0dd687271bbe25fef5ec94e03bd55c99e5f073d123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-020-04991-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-020-04991-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids></links><search><creatorcontrib>Karamova, A. E.</creatorcontrib><creatorcontrib>Semenova, V. G.</creatorcontrib><creatorcontrib>Verbenko, D. A.</creatorcontrib><creatorcontrib>Obraztsova, O. A.</creatorcontrib><creatorcontrib>Vanchugova, Kh. M.</creatorcontrib><creatorcontrib>Nikonorov, A. A.</creatorcontrib><creatorcontrib>Deryabin, D. G.</creatorcontrib><creatorcontrib>Solomka, V. S.</creatorcontrib><creatorcontrib>Kubanov, A. A.</creatorcontrib><title>Experimental Modeling of Leprosy in BALB/c, BALB/c Nude, CBA, and C57BL/6ТNF—/— Mice</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><description>Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF
—/—
mice using three
Mycobacterium leprae
strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of
M. leprae
of the used strains showed a temporal-quantitative dependence on the used mouse line. CBA and BALB/cNude mice were optimal for strain R and BALB/c and BALB/cNude lines were optimal for strain I. BALB/cNude mice infected with strain I had low lifespan.
M. leprae
strain M showed low proliferation activity in BALB/cNude and C57BL/6ТNF
—/—
mice.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Leprosy</subject><subject>Life span</subject><subject>Methods</subject><subject>Pathology</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kLFOwzAQhi0EEqXwAkyWWBhqYjtx7IxN1QJSWhYYmKzEuVSp0qTEjUQ3HoIn4Il4Bp4El1RCYmA4nU76_tPdh9AlozeMUulZRgWThHJKaBBFjMgjNGBC-kRxzo7RgDqKBEqpU3Rm7Wo_0pAN0PP0dQNtuYZ6m1Z43uRQlfUSNwVOYNM2dofLGsfjJPbM6NDxosthhCfxeITTOscTIePECz8_FrOvt3fPFZ6XBs7RSZFWFi4OfYieZtPHyR1JHm7vJ-OEGM6UJEooGRYSIDJ-angRZjQIsozmeagklyzLgIsCCgEmCoD6WS6EiSIQBZV-zrg_RNf9XnfuSwd2q9elNVBVaQ1NZzUPRMBoGDLh0Ks_6Krp2tpd5yjJhFB-JB3Fe8q4_20Lhd44QWm704zqvW3d29bOtv6xrfchvw9ZB9dLaH9X_5P6Bu5pf78</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Karamova, A. 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E.</au><au>Semenova, V. G.</au><au>Verbenko, D. A.</au><au>Obraztsova, O. A.</au><au>Vanchugova, Kh. M.</au><au>Nikonorov, A. A.</au><au>Deryabin, D. G.</au><au>Solomka, V. S.</au><au>Kubanov, A. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental Modeling of Leprosy in BALB/c, BALB/c Nude, CBA, and C57BL/6ТNF—/— Mice</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><date>2020-10-01</date><risdate>2020</risdate><volume>169</volume><issue>6</issue><spage>836</spage><epage>839</epage><pages>836-839</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><abstract>Leprosy was modeled in an experiment on BALB/c, BALB/cNude, CBA, and C57BL/6ТNF
—/—
mice using three
Mycobacterium leprae
strains obtained from patients with a diagnosis of A30 according to ICD-10 from different regions of the Russian Federation. Proliferation of
M. leprae
of the used strains showed a temporal-quantitative dependence on the used mouse line. CBA and BALB/cNude mice were optimal for strain R and BALB/c and BALB/cNude lines were optimal for strain I. BALB/cNude mice infected with strain I had low lifespan.
M. leprae
strain M showed low proliferation activity in BALB/cNude and C57BL/6ТNF
—/—
mice.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s10517-020-04991-7</doi><tpages>4</tpages></addata></record> |
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| subjects | Biomedical and Life Sciences Biomedicine Cell Biology Internal Medicine Laboratory Medicine Leprosy Life span Methods Pathology |
| title | Experimental Modeling of Leprosy in BALB/c, BALB/c Nude, CBA, and C57BL/6ТNF—/— Mice |
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