Cell salvage in burn excisional surgery
•Recovering erythrocytes during burn excisional surgery using cell salvage is feasible.•Blood saturated gauzes were washed in heparinized saline to recover shed blood.•The erythrocyte concentrate is of good quality and cost-effective.•Recovered erythrocytes show substantial bacterial contamination.•...
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Veröffentlicht in: | Burns 2021-02, Vol.47 (1), p.127-132 |
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Sprache: | eng |
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Zusammenfassung: | •Recovering erythrocytes during burn excisional surgery using cell salvage is feasible.•Blood saturated gauzes were washed in heparinized saline to recover shed blood.•The erythrocyte concentrate is of good quality and cost-effective.•Recovered erythrocytes show substantial bacterial contamination.•Percentage recovered erythrocytes increased with larger volume heparinized saline.
Hemostasis during burn surgery is difficult to achieve, and high blood loss commonly occurs. Bleeding control measures are limited, and many patients require allogeneic blood transfusions. Cell salvage is a well-known method used to reduce transfusions. However, its evidence in burns is limited. Therefore, this study aimed to examine the feasibility of cell salvage during burn surgery.
A prospective, observational study was conducted with 16 patients (20 measurements) scheduled for major burn surgery. Blood was recovered by washing saturated gauze pads with heparinized saline, which was then processed using the Cell Saver. Erythrocyte concentrate quality was analyzed by measuring hemoglobin, hematocrit, potassium, and free hemoglobin concentration. Microbial contamination was assessed based on cultures at every step of the process. Differences in blood samples were tested using the Student’s t-test.
The red blood cell mass recovered was 29 ± 11% of the mass lost. Patients’ preoperative hemoglobin and hematocrit levels were 10.5 ± 1.8 g/dL and 0.33 ± 0.05 L/L, respectively. The erythrocyte concentrate showed hemoglobin and hematocrit levels of 13.2 ± 3.9 g/dL and 0.40 ± 0.11 L/L thus showing a concentration effect. The potassium level was lower in the erythrocyte concentrate (2.5 ± 1.5 vs. 4.1 ± 0.4 mmol/L, p |
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ISSN: | 0305-4179 1879-1409 |
DOI: | 10.1016/j.burns.2020.06.030 |