Folic acid and vitamin B12 supplementation in subjects with type 2 diabetes mellitus: A multi-arm randomized controlled clinical trial

•Add-on vitamin B12 improved glycaemic control in patients with type 2 diabetes.•Median HbA1c change was – 1.2 % with vitamin B12 versus 0.3 % with control (p = 0.04).•Vitamin B12 also markedly improved insulin resistance & serum adiponectin (p 

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Veröffentlicht in:	Complementary therapies in medicine 2020-09, Vol.53, p.102526-102526, Article 102526
Hauptverfasser:	Satapathy, Swayamjeet, Bandyopadhyay, Debapriya, Patro, Binod Kumar, Khan, Shahnawaz, Naik, Sanjukta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Antidiabetics Biochemistry Blood pressure Clinical trials Cyanocobalamin Data collection Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetic neuropathy Dietary supplements Fasting Folic acid Glucose Homocysteine Insulin Insulin resistance Kinases Lipids Metabolism Patients Plasma Tumor necrosis factor-TNF Type 2 diabetes mellitus Vitamin B Vitamin B 12 Vitamin B12
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Beschreibung
Zusammenfassung:	•Add-on vitamin B12 improved glycaemic control in patients with type 2 diabetes.•Median HbA1c change was – 1.2 % with vitamin B12 versus 0.3 % with control (p = 0.04).•Vitamin B12 also markedly improved insulin resistance & serum adiponectin (p
ISSN:	0965-2299 1873-6963
DOI:	10.1016/j.ctim.2020.102526