Significant reductions in apoptosis-related proteins (HSPA6, HSPA8, ITGB3, YWHAH, and PRDX6) are involved in immune thrombocytopenia

To investigate differences in the expression of plasma proteins in immune thrombocytopenia (ITP) and normal control groups, bone marrow samples were collected from 20 active ITP patients and 20 healthy controls. Quantitative proteomics analysis based on mass spectrometry was used to measure the prot...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2021-05, Vol.51 (4), p.905-914
Hauptverfasser:	Liu, Shu-yan, Yuan, Dai, Sun, Rui-Jie, Zhu, Jing-jing, Shan, Ning-ning
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Apoptosis Bioinformatics Bone marrow Cardiac & Cardiovascular Systems Cardiology Cardiovascular System & Cardiology Hematology HSC70 Heat-Shock Proteins Humans Idiopathic thrombocytopenic purpura Integrin beta3 Life Sciences & Biomedicine Mass spectroscopy Medicine Medicine & Public Health Pathogenesis Peripheral Vascular Disease Peroxiredoxin VI Phosphatidylinositol 3-Kinases Plasma proteins Proteins Proteomes Proteomics Proto-Oncogene Proteins c-akt Purpura, Thrombocytopenic, Idiopathic Science & Technology Signal transduction Thrombocytopenia
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