Functional recovery in human partial thickness skin wounds after application of multicomponent hydrolipidic film (MAS063DP): A prospective, open‐label, comparative clinical trial
Acute and minor skin wounds are common in daily life. However, in clinical practice, after initial management in the acute phase, the wounds are managed mainly through observation, and the patients are usually lost to follow‐up. Considering a multicomponent hydrolipidic dressing (MAS063DP) long‐know...
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Veröffentlicht in: | Wound repair and regeneration 2021-01, Vol.29 (1), p.87-96 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Acute and minor skin wounds are common in daily life. However, in clinical practice, after initial management in the acute phase, the wounds are managed mainly through observation, and the patients are usually lost to follow‐up. Considering a multicomponent hydrolipidic dressing (MAS063DP) long‐known for its safe application in eczema and recently in laser‐induced wounds, we aimed to evaluate its ability in functional recovery of impaired skin integrity during wound healing. Sixteen patients (N = 16) were enrolled and completed (n = 8 vs n = 8) this prospective, open‐label, vehicle‐controlled clinical trial with 12‐week follow‐up. Transepidermal water, skin viscoelasticity and bioimpedance analysis were measured initially, at the 1st, 4th, 8th, and 12th weeks. Improvements in these parameters were greater in the MAS063DP group (from 31.4 ± 9.0 to 16.4 ± 4.3 g/m2 h, P |
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ISSN: | 1067-1927 1524-475X |
DOI: | 10.1111/wrr.12866 |