Gene regulation inference from single-cell RNA-seq data with linear differential equations and velocity inference

Abstract Motivation Single-cell RNA sequencing (scRNA-seq) offers new possibilities to infer gene regulatory network (GRNs) for biological processes involving a notion of time, such as cell differentiation or cell cycles. It also raises many challenges due to the destructive measurements inherent to...

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Veröffentlicht in:	Bioinformatics 2020-09, Vol.36 (18), p.4774-4780
Hauptverfasser:	Aubin-Frankowski, Pierre-Cyril, Vert, Jean-Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Profiling Gene Regulatory Networks RNA-Seq Sequence Analysis, RNA Single-Cell Analysis
Online-Zugang:	Volltext
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