SIS3, a good candidate for the reverse of type 2 diabetes mellitus in mice

TGF‐β signaling plays an extremely important role in the occurrence and development of type 2 diabetes mellitus (T2DM), and the blockade of TGF‐β/Smad3 pathway protests against the high‐fat diet‐induced obesity and diabetes. As a specific small molecule inhibitor of Smad3 protein, the biological act...

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Veröffentlicht in:	Fundamental & clinical pharmacology 2021-04, Vol.35 (2), p.389-396
Hauptverfasser:	Wang, Dao‐Cai, Yan, Ting‐Ting, Chen, Bin, Liu, Feng, Liu, Xiao‐Peng, Xie, Yong‐Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Blood glucose Body fat Body weight Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diet Glucose Glucose tolerance High fat diet Insulin Pharmacology SIS3 Smad3 inhibitor Smad3 protein treatment type 2 diabetes mellitus
Online-Zugang:	Volltext
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