Outcomes for children after second liver transplantations are similar to those after first transplantations: a binational registry analysis

Objective To assess long term graft and patient survival after donor liver retransplantation in children in Australia and New Zealand during 1986–2017; to determine the factors that influence survival. Design Retrospective cohort analysis (registry data). Setting, participants Australia and New Zeal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medical journal of Australia 2020-11, Vol.213 (10), p.464-470
Hauptverfasser: Jeffrey, Angus W, Jeffrey, Gary P, Stormon, Michael, Thomas, Gordon, O'Loughlin, Edward, Shun, Albert, Hardikar, Winita, Jones, Robert, McCall, John, Evans, Helen, Starkey, Graham, Hodgkinson, Peter, Ee, Looi C, Moore, David, Mews, Catherine, McCaughan, Geoff W, Angus, Peter W, Wigg, Alan J, Crawford, Michael, Fawcett, Jonathan
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Objective To assess long term graft and patient survival after donor liver retransplantation in children in Australia and New Zealand during 1986–2017; to determine the factors that influence survival. Design Retrospective cohort analysis (registry data). Setting, participants Australia and New Zealand Liver Transplant Registry data for all liver retransplantations in children (under 18 years of age), 1986–2017, in all four paediatric and six adult liver transplantation centres in the two countries. Main outcome measures Graft and patient survival at one, 5, 10 and 15 years. Results 142 liver retransplantations were undertaken in children (59 during 1986–2000, 83 during 2001–2017). Kaplan–Meier survival analysis indicated that survival was significantly greater during 2001–2017 than 1986–2000 (P 
ISSN:0025-729X
1326-5377
DOI:10.5694/mja2.50802