Outcomes for children after second liver transplantations are similar to those after first transplantations: a binational registry analysis
Objective To assess long term graft and patient survival after donor liver retransplantation in children in Australia and New Zealand during 1986–2017; to determine the factors that influence survival. Design Retrospective cohort analysis (registry data). Setting, participants Australia and New Zeal...
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Veröffentlicht in: | Medical journal of Australia 2020-11, Vol.213 (10), p.464-470 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objective
To assess long term graft and patient survival after donor liver retransplantation in children in Australia and New Zealand during 1986–2017; to determine the factors that influence survival.
Design
Retrospective cohort analysis (registry data).
Setting, participants
Australia and New Zealand Liver Transplant Registry data for all liver retransplantations in children (under 18 years of age), 1986–2017, in all four paediatric and six adult liver transplantation centres in the two countries.
Main outcome measures
Graft and patient survival at one, 5, 10 and 15 years.
Results
142 liver retransplantations were undertaken in children (59 during 1986–2000, 83 during 2001–2017). Kaplan–Meier survival analysis indicated that survival was significantly greater during 2001–2017 than 1986–2000 (P |
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ISSN: | 0025-729X 1326-5377 |
DOI: | 10.5694/mja2.50802 |