Calcium pantothenate is present in cosmetics and may cause allergic contact dermatitis

Calcium pantothenate (CAS no. 137‐08‐6) is the calcium salt of pantothenic acid (vitamin B5). It is used in cosmetics due to its anti‐static and hair conditioning properties. A 53‐year‐old female nurse's aide presented with intermittent facial eruptions (Figure S1). Patch tests were positive to calcium pantothenate, an ingredient of two of her products (a cleansing milk and a facial tonic). To our knowledge, no previous cases of sensitization from calcium pantothenate have been reported except for one case of systemic dermatitis from a nutritional supplement in a dexpanthenol‐sensitized patient.