Cognitive performance in midlife type 2 diabetes: results from the ENBIND study

Aims To establish the impact of uncomplicated type 2 diabetes on cognitive and neuropsychological performance in midlife. Methods We performed a cross‐sectional study of middle‐aged adults with uncomplicated type 2 diabetes and a cohort of healthy control participants. General cognition was assessed...

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Veröffentlicht in:	Diabetic medicine 2021-06, Vol.38 (6), p.e14412-n/a
Hauptverfasser:	Dyer, A. H., McKenna, L., Gamage, G., Bourke, N. M., Killane, I., Widdowson, M., Woods, C. P., Gibney, J., Reilly, R., O’Neill, D., Kennelly, S. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cognition & reasoning Cognition - physiology Cognitive ability Cognitive Dysfunction - epidemiology Cognitive Dysfunction - etiology Cognitive Dysfunction - psychology Cross-Sectional Studies Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - psychology Educational Status Female Follow-Up Studies Humans Incidence Ireland - epidemiology Male Memory - physiology Mental Status and Dementia Tests Middle age Middle Aged Neurology Neuropsychological Tests Neuropsychology Risk Factors Statistical analysis
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Zusammenfassung:	Aims To establish the impact of uncomplicated type 2 diabetes on cognitive and neuropsychological performance in midlife. Methods We performed a cross‐sectional study of middle‐aged adults with uncomplicated type 2 diabetes and a cohort of healthy control participants. General cognition was assessed using the Montreal Cognitive Assessment test and neuropsychological assessment was undertaken using a detailed neuropsychological assessment battery. Results A total of 152 participants (102 with type 2 diabetes and 50 controls) were recruited (mean age 52 ± 8 years, 51% women). Participants with midlife type 2 diabetes were more than twice as likely to make an error on the Montreal Cognitive Assessment test [incidence rate ratio 2.44 (95% CI 1.54 to 3.87); P
ISSN:	0742-3071 1464-5491
DOI:	10.1111/dme.14412