Serum Antibody Profile of a Patient With Coronavirus Disease 2019 Reinfection

We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were...

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Veröffentlicht in:Clinical infectious diseases 2021-05, Vol.72 (10), p.e659-e662
Hauptverfasser: To, Kelvin Kai-Wang, Hung, Ivan Fan-Ngai, Chan, Kwok-Hung, Yuan, Shuofeng, To, Wing-Kin, Tsang, Dominic Ngai-Chong, Cheng, Vincent Chi-Chung, Chen, Zhiwei, Kok, Kin-Hang, Yuen, Kwok-Yung
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Sprache:eng
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Zusammenfassung:We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa1368