Reversible switching from a three- to a nine-fold degenerate dynamic slider-on-deck through catenation

Two dynamic slider-on-deck assemblies, i.e. a two-component threefold degenerate ( k 298 = 34.9 kHz) and a catenated three-component ninefold degenerate ( k 298 = 27.9 kHz) system, were quantitatively interconverted. Inspection of their computed structures revealed an allosteric effect on the sliding rates due to the spatial interaction between the components. Two dynamic slider-on-deck assemblies, i.e. a two-component threefold degenerate ( k 298 = 34.9 kHz) and a catenated three-component ninefold degenerate ( k 298 = 27.9 kHz) system with allosteric effects on the sliding rates, were quantitatively interconverted.