Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance
An ancient resistance mechanism poses a problem when using streptogramin antibiotics. A modular approach to drug synthesis exploits this same mechanism to generate an antibiotic that avoids the emergence of resistance. A resistance-evading streptogramin antibiotic.
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| Veröffentlicht in: | Nature (London) 2020-10, Vol.586 (7827), p.32-33 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | An ancient resistance mechanism poses a problem when using streptogramin antibiotics. A modular approach to drug synthesis exploits this same mechanism to generate an antibiotic that avoids the emergence of resistance.
A resistance-evading streptogramin antibiotic. |
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| ISSN: | 0028-0836 1476-4687 |
| DOI: | 10.1038/d41586-020-02565-1 |