Linking human intestinal scaffolds and organoids to combat intestinal failure

Linking human intestinal scaffolds and organoids to combat intestinal failure

Combining organoids and decellularized intestinal scaffolds generates durable hybrid intestines that will open up new avenues for the regenerative treatment of patients with intestinal failure.

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Bibliographische Detailangaben
Veröffentlicht in:Nature medicine 2020-10, Vol.26 (10), p.1517-1518
Hauptverfasser: Fujii, Masayuki, Sugimoto, Shinya, Sato, Toshiro
Format: Artikel
Sprache:eng
Schlagworte:
631/61/490
692/699/1503/1581
Biomedical and Life Sciences
Biomedicine
Cancer Research
Care and treatment
Child
Colorectal diseases
Duodenum
Endothelium
Extracellular matrix
Fibroblasts
Gastrointestinal diseases
Health aspects
Humans
Infectious Diseases
Intestinal Mucosa
Intestine
Intestines
Jejunum
Metabolic Diseases
Molecular Medicine
Nervous system
Neurosciences
News & Views
news-and-views
Nutrients
Organoids
Patients
Pediatrics
Regenerative medicine
Scaffolds
Small intestine
Stem cells
Surgical anastomosis
Tissue culture
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Beschreibung
Zusammenfassung:Combining organoids and decellularized intestinal scaffolds generates durable hybrid intestines that will open up new avenues for the regenerative treatment of patients with intestinal failure.
ISSN:1078-8956
1546-170X
DOI:10.1038/s41591-020-1096-9