Neutrophil to lymphocyte ratio as a predictive biomarker for computed tomography scan use in mild traumatic brain injury

Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI. A retrospective study of adult patients who presented with mild-TBI One hundred and thi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biomarkers in medicine 2020-08, Vol.14 (12), p.1085-1090
Hauptverfasser: Alexiou, George A, Lianos, Georgios D, Tzima, Aggeliki, Sotiropoulos, Athanasios, Nasios, Anastasios, Metaxas, Dimitris, Zigouris, Andreas, Rn, Jolanda Zika, Mitsis, Michail, Voulgaris, Spyridon
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI. A retrospective study of adult patients who presented with mild-TBI One hundred and thirty patients met the inclusion criteria. Seventy-four patients had positive CT-findings. The mean NLR-levels at presentations were 5.6 ± 4.8. Patients with positive CT-findings had significant higher NLR-levels. Receiver operating characteristic curve analysis was conducted and the threshold of NLR-levels for detecting the cases with positive CT-findings was 2.5, with 78.1% sensitivity and 63% specificity To the best of our knowledge no previous study has assessed the value of NLR-levels for predicting the need for CT in mild-TBI.
ISSN:1752-0363
1752-0371
DOI:10.2217/bmm-2020-0150