Neutrophil to lymphocyte ratio as a predictive biomarker for computed tomography scan use in mild traumatic brain injury
Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI. A retrospective study of adult patients who presented with mild-TBI One hundred and thi...
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Veröffentlicht in: | Biomarkers in medicine 2020-08, Vol.14 (12), p.1085-1090 |
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Zusammenfassung: | Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI.
A retrospective study of adult patients who presented with mild-TBI
One hundred and thirty patients met the inclusion criteria. Seventy-four patients had positive CT-findings. The mean NLR-levels at presentations were 5.6 ± 4.8. Patients with positive CT-findings had significant higher NLR-levels. Receiver operating characteristic curve analysis was conducted and the threshold of NLR-levels for detecting the cases with positive CT-findings was 2.5, with 78.1% sensitivity and 63% specificity
To the best of our knowledge no previous study has assessed the value of NLR-levels for predicting the need for CT in mild-TBI. |
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ISSN: | 1752-0363 1752-0371 |
DOI: | 10.2217/bmm-2020-0150 |