A proposed gear mechanism for torque generation in the flagellar motor

In situ structures of the spirochete flagellar motor by cryo-ET reveal two distinct modes of interactions between the rotor ring and stator units. Together with new cryo-EM structures of the isolated stator units, this work provides insights into the mechanisms of torque generation and directional s...

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Veröffentlicht in:	Nature structural & molecular biology 2020-11, Vol.27 (11), p.1004-1006
1. Verfasser:	Namba, Keiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/535/1258/1259 631/535/1258/1260 Bacteria - metabolism Bacteria - ultrastructure Bacterial Infections - microbiology Bacterial Proteins - metabolism Bacterial Proteins - ultrastructure Biochemistry Biological Microscopy Biomedical and Life Sciences Cells Cryoelectron Microscopy Flagella Flagella (Microbiology) Flagella - metabolism Flagella - ultrastructure Flagellin - metabolism Flagellin - ultrastructure Humans Life Sciences Lipids Membrane Biology Molecular biology Motility News & Views news-and-views Properties Protein Structure Proteins Spirochaetales - metabolism Spirochaetales - ultrastructure Spirochetes Stators Torque
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Beschreibung
Zusammenfassung:	In situ structures of the spirochete flagellar motor by cryo-ET reveal two distinct modes of interactions between the rotor ring and stator units. Together with new cryo-EM structures of the isolated stator units, this work provides insights into the mechanisms of torque generation and directional switch.
ISSN:	1545-9993 1545-9985
DOI:	10.1038/s41594-020-00514-0