Combination of autoimmune pancreatitis and peripheral neuropathy on an IgG4-related disease patient with 4 years following-up

Type1 autoimmune pancreatitis (AIP) is the first recognized and the most common manifestation of IgG4-related disease. However, AIP patient presented with neuropathy in the extremities have not been reported previously. We reported a rare combination of autoimmune pancreatitis and peripheral neuropathy on an IgG4-related disease patient based on histological features to expand the clinical spectrum of IgG4-related disease. [Display omitted] •IgG4-related disease is an immune-mediated disease.•Type 1 autoimmune pancreatitis is the pancreatic manifestation and the most common subtype.•IgG4-related peripheral neuropathy is rarely reported.•IgG4-related disease should be taken into consideration when patients have peripheral neuropathy and multi-organ involvement at the same time.