Lesion Age Imaging in Acute Stroke: Water Uptake in CT Versus DWI‐FLAIR Mismatch

Lesion Age Imaging in Acute Stroke: Water Uptake in CT Versus DWI‐FLAIR Mismatch

Purpose In acute ischemic stroke with unknown time of onset, magnetic resonance (MR)‐based diffusion‐weighted imaging (DWI) and fluid‐attenuated inversion recovery (FLAIR) estimates lesion age to guide intravenous thrombolysis. Computed tomography (CT)‐based quantitative net water uptake (NWU) may b...

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Veröffentlicht in:Annals of neurology 2020-12, Vol.88 (6), p.1144-1152
Hauptverfasser: Broocks, Gabriel, Leischner, Hannes, Hanning, Uta, Flottmann, Fabian, Faizy, Tobias D., Schön, Gerhard, Sporns, Peter, Thomalla, Götz, Kamalian, Shahmir, Lev, Michael H., Fiehler, Jens, Kemmling, Andre
Format: Artikel
Sprache:eng
Schlagworte:
Age
Aged
Computed tomography
Confidence intervals
Diffusion Magnetic Resonance Imaging - methods
Empirical analysis
Female
Humans
Intravenous administration
Ischemia
Lesions
Magnetic resonance imaging
Male
Medical imaging
Middle Aged
Regression analysis
Resonance
Sensitivity
Signal classification
Statistical analysis
Stroke
Stroke - metabolism
Thrombolysis
Thrombolytic Therapy - methods
Time Factors
Tomography, X-Ray Computed - methods
Water - metabolism
Water uptake
Windows (intervals)
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Zusammenfassung:Purpose In acute ischemic stroke with unknown time of onset, magnetic resonance (MR)‐based diffusion‐weighted imaging (DWI) and fluid‐attenuated inversion recovery (FLAIR) estimates lesion age to guide intravenous thrombolysis. Computed tomography (CT)‐based quantitative net water uptake (NWU) may be a potential alternative. The purpose of this study was to directly compare CT‐based NWU to magnetic resonance imaging (MRI) at identifying patients with lesion age
ISSN:0364-5134
1531-8249
DOI:10.1002/ana.25903