Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma

Purpose Temporal muscle thickness (TMT) has been suggested as a novel biomarker that can represent sarcopenia in head and neck malignancies. This study investigated the association of TMT with clinical outcomes in patients with newly diagnosed glioblastoma (GBM). Methods Using electronic medical rec...

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Veröffentlicht in:Journal of cancer research and clinical oncology 2021-03, Vol.147 (3), p.901-909
Hauptverfasser: An, Geon, Ahn, Stephen, Park, Jae-Sung, Jeun, Sin- Soo, Hong, Yong- Kil
Format: Artikel
Sprache:eng
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Zusammenfassung:Purpose Temporal muscle thickness (TMT) has been suggested as a novel biomarker that can represent sarcopenia in head and neck malignancies. This study investigated the association of TMT with clinical outcomes in patients with newly diagnosed glioblastoma (GBM). Methods Using electronic medical records, all GBM patients between 2008 and 2018 at Seoul St. Mary’s Hospital were reviewed. Total 177 patients met our eligibility criteria. Results The thinner group who had TMT less than the median showed shorter overall survival (OS) and progression-free survival (PFS) than the thicker group who had TMT more than median (OS; 11.0 versus 18.0 months, p  
ISSN:0171-5216
1432-1335
DOI:10.1007/s00432-020-03386-5