In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves

[Display omitted] •Angiogenesis is a “hallmark” of cancer.•Extracts from Spondias mombin L. have shown a wide range of biological effects.•Phenols are important components that may play a role in those biological effects.•Effects of the extracts were tested in several biological assays.•Extracts have displayed an effect over cellssurvival and angiogenetic potential. The traditional ethnobotanic and pharmacologic use of Spondias mombin L. samples includes a wide range of applications. In the present study, new antiangiogenic and antitumor effects of two types of extracts from Spondias mombin L. leaves have been demonstrated by using a number of in vitro assays in both endothelial and human cancer and non cancer cells.