Meta-Analysis Comparing Angiography-Guided Versus FFR-Guided Coronary Artery Bypass Grafting

FFR-guided decision making for percutaneous coronary intervention (PCI) has showed improved outcomes compared with angiography alone.1 It remains unknown if such an approach can improve outcomes for coronary artery bypass grafting (CABG). The FAME trial showed that in comparison with angiography alone, FFR-guided PCI reduced the rate of the composite end point of death, nonfatal myocardial infarction, and repeat revascularization.1 PCI and CABG are different forms of revascularization and this study shows FFR guidance data from PCI cannot be extrapolated to CABG. [...]use of FFR guidance for CABG revascularization decision making compared with angiography alone may result in better graft patency but clinical outcomes are similar.Disclosures The authors have no conflicts of interest to disclose.