Infliximab for the treatment of recalcitrant bullous Sweet syndrome in a 10‐year‐old girl

Infliximab for the treatment of recalcitrant bullous Sweet syndrome in a 10‐year‐old girl

We report the case of a 10‐year‐old girl with bullous Sweet syndrome, recalcitrant to high‐dose systemic corticosteroids. Subsequent treatment with infliximab resulted in a rapid improvement in cutaneous lesions and systemic symptoms. Cutis laxa was noted in the healed skin. We propose early second‐...

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Veröffentlicht in:Pediatric dermatology 2020-11, Vol.37 (6), p.1183-1184
Hauptverfasser: Knöpfel, Nicole, Theiler, Martin, Luchsinger, Isabelle, Hafner, Bettina, Brunner, Corinne, Kolm, Isabel, Weibel, Lisa
Format: Artikel
Sprache:eng
Schlagworte:
acute febrile neutrophilic dermatosis
bullous Sweet syndrome
cardiovascular elastolysis
Case reports
Child
Corticosteroids
Cutis Laxa
Dermatology
Female
Humans
Immunotherapy
Infliximab
Infliximab - therapeutic use
Monoclonal antibodies
Pediatrics
postinflammatory cutis laxa
Skin
Skin diseases
Sweet Syndrome - diagnosis
Sweet Syndrome - drug therapy
Sweet's syndrome
TNF inhibitors
Tumor necrosis factor-α
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Zusammenfassung:We report the case of a 10‐year‐old girl with bullous Sweet syndrome, recalcitrant to high‐dose systemic corticosteroids. Subsequent treatment with infliximab resulted in a rapid improvement in cutaneous lesions and systemic symptoms. Cutis laxa was noted in the healed skin. We propose early second‐line treatment with infliximab in children with steroid‐refractory Sweet syndrome.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.14356