Topical cidofovir for the treatment of recalcitrant viral warts and molluscum contagiosum in Jacobsen syndrome

Jacobsen syndrome is caused by a terminal deletion on the long arm of chromosome 11 and can be associated with immunodeficiency. Patients with Jacobsen syndrome can be predisposed to cutaneous viral infections that are difficult to treat. We report successful use of topical 1% cidofovir as treatment...

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Veröffentlicht in:Pediatric dermatology 2020-11, Vol.37 (6), p.1191-1192
Hauptverfasser: Alsaleemi, Ali, O’Connor, Cathal, Irvine, Alan D., Leahy, Timothy Ronan
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Sprache:eng
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Zusammenfassung:Jacobsen syndrome is caused by a terminal deletion on the long arm of chromosome 11 and can be associated with immunodeficiency. Patients with Jacobsen syndrome can be predisposed to cutaneous viral infections that are difficult to treat. We report successful use of topical 1% cidofovir as treatment of recalcitrant verruca vulgaris in one patient and molluscum contagiosum in another patient with Jacobsen syndrome. Topical cidofovir appears to be a good treatment option in this cohort and should be considered early for treatment‐resistant cutaneous viral infections.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.14355