Impact of high-dose statin on cardiovascular outcomes in real-world patients with ST-elevation acute myocardial infarction

Little is known about the impact of a high-dose statin on cardiovascular outcomes after ST-elevation acute myocardial infarction (STEMI) in real-world Japanese patients. Between July 2011 and June 2017, 1110 consecutive STEMI patients underwent primary percutaneous coronary intervention at our hospi...

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Veröffentlicht in:	Heart and vessels 2021-03, Vol.36 (3), p.297-307
Hauptverfasser:	Shimada, Takenobu, Osakada, Kohei, Okabe, Koya, Shima, Yuki, Eguchi, Haruki, Habara, Seiji, Tada, Takeshi, Taguchi, Yuya, Ikuta, Akihiro, Takamatsu, Makoto, Murai, Ryosuke, Miura, Katsuya, Ohya, Masanobu, Amano, Hidewo, Kubo, Shunsuke, Tanaka, Hiroyuki, Maruo, Takeshi, Fuku, Yasushi, Katoh, Harumi, Goto, Tsuyoshi, Kadota, Kazushige
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical Engineering and Bioengineering Cardiac Surgery Cardiology Cerebral infarction Cholesterol Confidence intervals Density Dosage Heart attacks Ischemia Lesions Medicine Medicine & Public Health Myocardial infarction Original Article Statins Vascular Surgery
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Zusammenfassung:	Little is known about the impact of a high-dose statin on cardiovascular outcomes after ST-elevation acute myocardial infarction (STEMI) in real-world Japanese patients. Between July 2011 and June 2017, 1110 consecutive STEMI patients underwent primary percutaneous coronary intervention at our hospital and were discharged. A high-dose statin was administered in 117 patients (10.5%) and non-high-dose statin was administered in 947 patients (85.3%). The low-density lipoprotein cholesterol level was significantly higher in the high-dose statin group at admission (129.8 ± 44.9 vs. 110.4 ± 32.7, p
ISSN:	0910-8327 1615-2573
DOI:	10.1007/s00380-020-01696-9