Open-Label placebo for the treatment of unipolar depression: Results from a randomized controlled trial

Open-Label placebo for the treatment of unipolar depression: Results from a randomized controlled trial

•We assessed the efficacy of open label placebo (OLP) in the setting of a randomized controlled trial as an add-on treatment for depression.•There was an overall decrease in depression levels over time among our entire study sample•Our findings support the possibility that OLP is an effective treatm...

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Veröffentlicht in:Journal of affective disorders 2020-11, Vol.276, p.707-710
Hauptverfasser: Nitzan, Uri, Carmeli, Gal, Chalamish, Yossi, Braw, Yoram, Kirsch, Irving, Shefet, Daphna, Krieger, Israel, Mendlovic, Shlomo, Bloch, Yuval, Lichtenberg, Pesach
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Antidepressants
Antidepressive Agents - therapeutic use
Child, Preschool
Clinical practice
Depression
Depression - drug therapy
Depressive Disorder - drug therapy
Double-Blind Method
Female
Humans
Infant
Male
Placebo
Placebo Effect
Treatment Outcome
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Zusammenfassung:•We assessed the efficacy of open label placebo (OLP) in the setting of a randomized controlled trial as an add-on treatment for depression.•There was an overall decrease in depression levels over time among our entire study sample•Our findings support the possibility that OLP is an effective treatment for non-geriatric patients (
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2020.07.077