Sclerotinia sclerotiorum Infection Triggers Changes in Primary and Secondary Metabolism in Arabidopsis thaliana

is a devastating plant pathogen that causes substantial losses in various agricultural crops. Although plants have developed some well-known defense mechanisms against invasive fungi, much remains to be learned about plant responses to fungal pathogens. In this study, we investigated how infection affects plant primary and secondary metabolism in the model plant . Our results showed that soluble sugar and amino acid content changed significantly in leaves upon fungal colonization, with a decrease in sucrose and an increase in mannitol, attributed to fungal biosynthesis. Furthermore, the jasmonate signaling pathway was rapidly activated by infection, and there was a striking accumulation of antifungal metabolites such as camalexin, -coumaroyl agmatine, feruloyl agmatine, and -acetylornithine. On the other hand, the characteristic defense compounds of the Brassicaceae, the glucosinolates, were not induced in infected by . Our study provides a better understanding of how primary and secondary metabolism is modified during infection by a fungal pathogen like that has both hemibiotrophic and necrotrophic stages.