Monolithic Poly(styrene-co-divinylbenzene) Columns for Supercritical Fluid Chromatography–Mass Spectrometry Analysis of Polypeptide

The organic polymer-based monolithic columns have been evaluated as the separation media for analysis of peptides using supercritical fluid chromatography–mass spectrometry (SFC–MS). We demonstrate for the first time the SFC–MS separation of a mixture of polypeptides carried out using poly(styrene-...

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Veröffentlicht in:	Analytical chemistry (Washington) 2020-09, Vol.92 (17), p.11525-11529
Hauptverfasser:	Zajickova, Zuzana, Nováková, Lucie, Svec, Frantisek
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Biosensing Techniques Carbon dioxide Carbon Dioxide - chemistry Chemistry Chromatography Chromatography, High Pressure Liquid Chromatography, Supercritical Fluid - methods Divinylbenzene Elution Gramicidin Gramicidin - analysis Gramicidin - isolation & purification Ionization Ions Isoforms Mass spectrometry Mass spectroscopy Methanol Methanol - chemistry Molecular Weight Peptides Polymers Polypeptides Polystyrene resins Polystyrenes - chemistry Porosity Protein Isoforms - chemistry Scientific imaging Separation Spectrometry, Mass, Electrospray Ionization Spectroscopy Styrene Styrenes Supercritical fluids Temperature
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