Tolvaptan treatment in hyponatremia due to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): effects on survival in patients with cancer

Tolvaptan treatment in hyponatremia due to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): effects on survival in patients with cancer

Purpose To investigate the clinical outcomes of patients with hyponatremia who received supportive treatment or tolvaptan plus supportive treatment and the effects of treatment and other variables on overall survival Methods This study included oncology patients who were hospitalized at two oncology...

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Veröffentlicht in:International urology and nephrology 2021-02, Vol.53 (2), p.301-307
Hauptverfasser: Bilgetekin, Irem, Erturk, Ismail, Basal, Fatma Bugdayci, Karacin, Cengiz, Karadurmus, Nuri, Oksuzoglu, Berna, Demirci, Umut
Format: Artikel
Sprache:eng
Schlagworte:
Antidiuretics
Hyponatremia
Medicine
Medicine & Public Health
Nephrology
Nephrology - Original Paper
Oncology
Patients
Sodium
Statistical analysis
Survival
Urology
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Zusammenfassung:Purpose To investigate the clinical outcomes of patients with hyponatremia who received supportive treatment or tolvaptan plus supportive treatment and the effects of treatment and other variables on overall survival Methods This study included oncology patients who were hospitalized at two oncology centers between January 1, 2016 and December 31, 2019 for hyponatremia (sodium levels  0.05). In the TpST group, recovery days of the hyponatremia after treatment and the length of hospital stay was shorter and hyponatremia symptoms and hospital complications were less frequent compared to the ST group ( p  
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-020-02623-7