Application of Molecularly Imprinted Polymer-modified Potentiometric Sensor for Quantitative Determination of Histamine in Serum

A molecularly imprinted polymer-modified potentiometric histamine (HIS) sensor was prepared and used for quantitative determination of HIS in bovine serum. The calibration curve using the potential responses measured in 1 × 10−3 mol L−1 phosphate buffer (pH 7.4) showed good linearity in the HIS conc...

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Veröffentlicht in:Analytical Sciences 2020/12/10, Vol.36(12), pp.1561-1563
Hauptverfasser: KONISHI, Atsuko, TAKEGAMI, Shigehiko, IDOSAKI, Yoko, KITADE, Tatsuya
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container_issue 12
container_start_page 1561
container_title Analytical Sciences
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creator KONISHI, Atsuko
TAKEGAMI, Shigehiko
IDOSAKI, Yoko
KITADE, Tatsuya
description A molecularly imprinted polymer-modified potentiometric histamine (HIS) sensor was prepared and used for quantitative determination of HIS in bovine serum. The calibration curve using the potential responses measured in 1 × 10−3 mol L−1 phosphate buffer (pH 7.4) showed good linearity in the HIS concentration range of 3 × 10−4 to 1 × 10−2 mol L−1 (r = 0.92), with a detection limit of 1.6 × 10−4 mol L−1. In bovine serum samples, the HIS sensor showed good recovery values of 91 – 104%. Therefore, this HIS sensor successfully determined the HIS concentration in bovine serum samples.
doi_str_mv 10.2116/analsci.20N018
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subjects Analytical Chemistry
Animals
Blood Chemical Analysis - instrumentation
Calibration
Cattle
Chemistry
Histamine
Histamine - blood
Hydrogen-Ion Concentration
Imprinted polymers
Limit of Detection
Linearity
molecularly imprinted polymer
Molecularly Imprinted Polymers - chemistry
Polymers
Potentiometric sensor
Potentiometry - instrumentation
quantitative determination
selectivity
Sensors
serum
title Application of Molecularly Imprinted Polymer-modified Potentiometric Sensor for Quantitative Determination of Histamine in Serum
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