Long-term follow-up of patients undergoing decompressive hemicraniectomy for malignant stroke: Quality of life and caregiver’s burden in a real-world setting
•We evaluated survival rates, quality of life, daily activities, and caregiver burden in patients with decompressive craniectomy for stroke.•Mortality rate was higher among older patients.•Age was a determining factor for functional outcome but not for quality of life.•The caregiver burden was signi...
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Veröffentlicht in: | Clinical neurology and neurosurgery 2020-10, Vol.197, p.106168-106168, Article 106168 |
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Sprache: | eng |
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Zusammenfassung: | •We evaluated survival rates, quality of life, daily activities, and caregiver burden in patients with decompressive craniectomy for stroke.•Mortality rate was higher among older patients.•Age was a determining factor for functional outcome but not for quality of life.•The caregiver burden was significantly correlated with the severity of disability and age.•Some patients reported having a reasonable quality of life, regardless of their degree of disability.
Decompressive hemicraniectomy is a life-saving procedure for the treatment of space-occupying middle cerebral artery infarctions (malignant stroke); however, patients may survive severely disabled. Comprehensive data on long-term sequelae outside randomized controlled trials are scarce.
We retrospectively evaluated the survival rates, quality of life, ability to perform activities of daily living, and caregiver burden of 61 patients (aged from 37 to 83) who had previously undergone decompressive hemicraniectomy for malignant stroke between 2012 and 2017.
The mortality rate was higher among patients older than 60 years than among younger patients (71.0 % vs 36.7 %, p = 0.007; odds ratio 4.222, 95 % confidence interval 1.443–12.355). The mean survival time was 37.9 ± 6.0 months for 19 survivors of the younger group and 22.6 ± 5.7 months for 9 survivors of the older group. Among the 28 surviving patients, 22 (78.6 %) were interviewed, and we found that age was a determining factor for functional outcome (Barthel indices of 65.7 ± 10.6 for younger patients vs 48.0 ± 9.3 for older patients, p |
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ISSN: | 0303-8467 1872-6968 |
DOI: | 10.1016/j.clineuro.2020.106168 |