Mania triggered by levodopa treatment in a patient with frontotemporal dementia caused by A C9orf72 repeat expansion: A case report

Mania triggered by levodopa treatment in a patient with frontotemporal dementia caused by A C9orf72 repeat expansion: A case report

•The C9orf72 repeat expansion is a common cause of frontotemporal dementia.•Parkinsonism develops in a substantial number of patients with C9orf72 associated frontotemporal dementia.•C9orf72 associated frontotemporal dementia may be linked to mania and bipolar disease.

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Bibliographische Detailangaben
Veröffentlicht in:Clinical neurology and neurosurgery 2020-11, Vol.198, p.106147-106147, Article 106147
Hauptverfasser: Thorlacius-Ussing, Gorm, Nielsen, Jørgen E., Law, Ian, Hansen, Hanne Vibe, Birgitte Bo, Andersen
Format: Artikel
Sprache:eng
Schlagworte:
Affective disorders
Amyotrophic lateral sclerosis
Bipolar disorder
Brain diseases
C9orf72
Case reports
Dementia
Dementia disorders
Disease
Dopamine
Drug dosages
Drug withdrawal
Executive function
Frontotemporal dementia
Hallucinations
Heredity
Hyperactivity
Levodopa
Lithium
Mania
Movement disorders
Neurodegeneration
Neurodegenerative diseases
Neurology
Parkinson's disease
Parkinsonism
Patients
Psychosis
Psychotropic drugs
Tremor
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Beschreibung
Zusammenfassung:•The C9orf72 repeat expansion is a common cause of frontotemporal dementia.•Parkinsonism develops in a substantial number of patients with C9orf72 associated frontotemporal dementia.•C9orf72 associated frontotemporal dementia may be linked to mania and bipolar disease.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2020.106147