Water-soluble oligofluorenes bearing N1-alkylcytosine side chains as turn-on and turn-off materials in telomere DNA length sensing

Water-soluble oligofluorenes bearing N1-alkylcytosine side chains as turn-on and turn-off materials in telomere DNA length sensing

Water-soluble cationic and anionic oligofluorenes bearing N1-alkylcytosine side chains, namely OF-1 and OF-2, were synthesized. The photoluminescence (PL) intensity of an aqueous solution of OF-1 decreased on the addition of (TTAGGG)m as telomere DNA models. In contrast, the PL intensity of OF-2 inc...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-01, Vol.56 (74), p.10914-10917
Hauptverfasser: Yamaguchi, Isao, Ooe, Ryoga, Wang, Aohan
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
Aqueous solutions
Chains
Deoxyribonucleic acid
DNA
Photoluminescence
Water chemistry
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Zusammenfassung:Water-soluble cationic and anionic oligofluorenes bearing N1-alkylcytosine side chains, namely OF-1 and OF-2, were synthesized. The photoluminescence (PL) intensity of an aqueous solution of OF-1 decreased on the addition of (TTAGGG)m as telomere DNA models. In contrast, the PL intensity of OF-2 increased on the addition of DNA.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc05153e